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Saturday, November 21, 2009 9:12 AM

Published 11/06/2009 by HIV and Hepatitis.com


Entecavir (Baraclude) Demonstrates Greater Antiviral Activity than Adefovir (Hepsera) in Hepatitis B Patients with Decompensated Liver Disease

To explore this issue, an international team of investigators conducted a randomized, open-label, Phase 3b study (ETV-048) comparing 1.0 mg/day entecavir versus 10 mg/day adefovir in this population. A total of 100 participants randomly assigned to the...

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What others report on the same story

Tenofovir (Viread) Regimens Are Effective and W...
Over years or decades, can lead to decompensated liver disease, characterized by symptoms such as ascites (abdominal fluid accumulation), portal vein hypertension, ... - [11/06/2009 - HIV and Hepatitis.com]

Quotes

...C liver disease. "This study represents an important first step in addressing an unmet medical need, as this is one of the first comparative studies to evaluate the safety and efficacy of antiviral therapy in this difficult-to-treat patient population" said ETV-048 study...
Entecavir (Baraclude) Demonstrates Greater Antiviral Activity than Adefovir (Hepsera) in Hepatiti ... [HIV and Hepatitis.com - 11/06/2009]
...stol-Myers Squibb. "Chronic hepatitis B is a lifelong disease and these data suggest that treatment with Baraclude may offer patients with decompensated cirrhosis a treatment option." Chang Gung Memorial...
Entecavir (Baraclude) Demonstrates Greater Antiviral Activity than Adefovir (Hepsera) in Hepatiti ... [HIV and Hepatitis.com - 11/06/2009]

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Influenza Round Table: Antiviral Drugs [CDC Streaming Health - YouTube - 10/30/2009]
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