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Saturday, November 21, 2009 10:45 PM

Published 11/03/2009 by Yahoo! Canada


INFORM-1 Results: Robust Antiviral Suppression Achieved with Combination of Nucleoside Analog Polymerase Inhibitor RG7128 and Protease Inhibitor RG722

BOSTON, Nov. 3 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN) and Pharmasset, Inc. (Nasdaq: VRUS) today announced results from all patient cohorts of the INFORM-1 trial, an innovative Phase 1 study of two direct-acting antiviral (DAA) compounds administered without interferon...

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What others report on the same story

INFORM-1 Results: Robust Antiviral Suppression ...
--- Significant antiviral potency in both naive and treatment-failure patients ---- Promising Safety and Tolerability ---- Phase 2 studies to begin in Q1 2010 -BOSTON, ... - [11/03/2009 - Individual.com]
AASLD: New Drug Boosts HCV Clearance
BOSTON -- Most hepatitis C patients who are initially unresponsive to standard therapy were able to achieve sustained virologic responses when the investigational ... - [11/03/2009 - MedPage Today]
Combination Drugs Are The Future for Hepatitis C
Biotech , Hepatitis C , HIV Steve Worland wrote:Combination therapy has been a central component of treatment for certain viral diseases for more than 15 years. ... - [11/03/2009 - Xconomy]

Quotes

...Gane commented, "The results from this study of the RG7227/RG7128 combination raise hopes that we can deliver an interferon-free regimen for our patients in the future. Current HCV therapy includes up to 12 months of weekly interferon injections which can be associated with significant side effects. In addition, not all patients can take interferon due to intolerance or contraindications. We look forward to the results of additional studies with these potent compounds."
INFORM-1 Results: Robust Antiviral Suppression Achieved with Combination of Nucleoside Analog Pol ... [Yahoo! Canada - 11/03/2009]
(i) "Combination Therapy with a Nucleoside Polymerase (RG7128) and Protease (RG7227/ITMN-191) Inhibitor Combination in HCV: Safety, Pharmacokinetics, and Virologic Results from INFORM-1" Abstract #193: to be...
INFORM-1 Results: Robust Antiviral Suppression Achieved with Combination of Nucleoside Analog Pol ... [Yahoo! Canada - 11/03/2009]

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Influenza Round Table: Antiviral Drugs [CDC Streaming Health - YouTube - 10/30/2009]
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