Nuclease

Type: Keyphrase

Name: Nuclease

First Reported Mar 10 2010 - Updated Mar 11 2010 - 1 Documents

Biosearch Seeks to Enter IVD Market with Expanded Roche License

Biosearch Technologies has taken an important step toward entering the in vitro diagnostics market by expanding its license with Roche Molecular Systems in the area of nucleic acid amplification technologies, the company said this week.Under the new license, ... [Published Mar 10 2010 by GenomeWeb]

Entities: Diagnostic, Nuclease, Assay

First Reported Mar 08 2010 - Updated Mar 09 2010 - 1 Documents

Knockout Rats for ADME-Tox Applications

Sigma Life Science extended its portfolio of knockout rat models with the announcement of a new suite of models designed to facilitate more predictive absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox) studies. This extension of ... [Published Mar 08 2010 by Bioscience Technology Online]

Entities: Rats, Protein, Pregnane, P-glycoprotein

First Reported Feb 11 2010 - Updated Feb 11 2010 - 1 Documents

The triple helix: 50 years later, the outcome.

Triplex-forming oligonucleotides constitute an interesting DNA sequence-specific tool that can be used to target cleaving or cross-linking agents, transcription factors or nucleases to a chosen site on the DNA. They are not only used as biotechnological ... [Published Feb 11 2010 by Research & Development]

Entities: DNA, Nuclease, Biotechnology

First Reported Feb 09 2010 - Updated Feb 09 2010 - 1 Documents

Citations

There are no surefire options for making large, targeted deletions in mammalian cells. In murine embryonic stem (ES) cells, it's possible to insert two Flp recombinase target (FRT) or loxP sites in the genome and then introduce Flp or Cre recombinase ... [Published Feb 09 2010 by Bio Techniques]

Entities: Protein, Genome, Zinc Finger, Nuclease

First Reported Feb 08 2010 - Updated Feb 08 2010 - 1 Documents

University of Bristol

Reports outline life sciences study results from University of Bristol, Department of Biochemistry

Researchers detail in 'DNA cleavage and methylation specificity of the single polypeptide restriction-modification enzyme LlaGI,' new data in life sciences. 'LlaGI is a single polypeptide restriction-modification enzyme encoded on the naturally-occurring ... [Published Feb 08 2010 by Poten & Partners]

Entities: Polypeptide, University of Bristol, Enzyme, Biochemistry, DNA

First Reported Jan 15 2010 - Updated Jan 15 2010 - 1 Documents

Sangamo BioSciences Initiates ZFP Therapeutics Clinical Trial

Sangamo BioSciences (Sangamo) has initiated two new clinical trials of ZFP Therapeutics, a phase 2b study in diabetic neuropathy (DN) and a phase 1 trial in glioblastoma. The company has also received renewal of $3m in funding for the phase 2b trial by ... [Published Jan 15 2010 by Pharmaceutical Business Review]

Entities: Sangamo BioSciences Inc, glucocorticoid, glioblastoma

First Reported Dec 08 2009 - Updated Dec 09 2009 - 1 Documents

Transgenomic Announces the Commercial Launch of SURVEYOR(R) Scan K-RAS Mutation Detection Kit

OMAHA, Neb., Dec. 8 /PRNewswire-FirstCall/ -- Transgenomic, Inc. (OTC Bulletin Board: TBIO) announced today the launch of its SURVEYOR Scan K-RAS kit, the first in a family of mutation detection kits the company plans to offer featuring its proprietary ... [Published Dec 08 2009 by Financial Services]

Entities: Transgenomic Incorporated, Mutation, Nuclease, DNA, Heteroduplex DNA

Quotes

...Marc Beal, director of Corporate Development at Biosearch Technologies, comments, "On September 16th, 2009, Biosearch took licenses to Roche patents covering practice of the 5' Nuclease process, and later in the year, licensed the CDC patents describing the 2009 H1N1 and Influenza A Sub-typing signatures. With this expanded Roche license, Biosearch is poised to enter the IVD marketplace as a pivotal manufacturer of diagnostic kits." As the inventor and patent holder of the BHQ (Black Hole Quencher), CAL Fluor, and Quasar dye technologies, Biosearch is the sole source offering access...

Biosearch expands licensing pact with Roche to manufacture & sell in-vitro diagnostic kits [PharmaBiz - Mar 12 2010]

Biosearch added that the series of BHQ dyes have become "an essential component in the highest performing, frequently demanded qPCR assays in the IVD market, including the original 2009 H1N1 influenza assays purchased by public health and other qualified laboratories worldwide."

Biosearch Seeks to Enter IVD Market with Expanded Roche License [GenomeWeb - Mar 10 2010]

...polymerase chain reaction (PCR) methods and instrumentation, including the 5' Nuclease process and the use of SYBR Green I in PCR reactions. "This agreement demonstrates both companies' commitments to advancing quality research in the applied and life science fields. It also enables innovation in a more open environment that is good for business and ultimately benefits customers" said Randy Rasmussen, president of Idaho Technology, in a statement

Applied Biosystems and Idaho Technology enter into cross-licensing agreement [Drug Discovery News - Mar 09 2010]

More Content

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Sigma introduces knockout rats for ADME/Tox app... [Life Science Lab - 3 hours ago]
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Biosearch Technologies Expands Licensing of Roc... [Clinical Lab Products - Mar 11 2010]
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Applied Biosystems and Idaho Technology enter i... [Drug Discovery News - Mar 09 2010]
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Sigma-Aldrich New Life Science Brand [Drug Discovery World - Mar 08 2010]
Knockout Rats for ADME-Tox Applications [Bioscience Technology Online - Mar 08 2010]
Precision BioSciences Announces that the US Pat... [Forbes.com - Mar 08 2010]
Precision BioSciences Announces that the US Pat... [PR inside - Mar 08 2010]
Precision BioSciences Announces that the US Pat... [Earthtimes.org - Mar 08 2010]
Sigma Life Science extends portfolio of knockou... [News-Medical.Net - Mar 08 2010]
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Sigma-Aldrich unveils new Sigma Life Science br... [News-Medical.Net - Mar 02 2010]
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IDT qPCR offers more customised screening [Life Science Lab - Mar 01 2010]
Senior Independent Director [FinanzNachrichten.de - Feb 12 2010]
The triple helix: 50 years later, the outcome. [Research & Development - Feb 11 2010]
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Study validates Transgenomic's COLD-PCR technol... [News-Medical.Net - Feb 09 2010]
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Transgenomic Demonstrates Very High Sensitivity... [Forbes.com - Feb 08 2010]
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